Congenital Thrombotic Risk Factors in β-Thalassemia

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منابع مشابه

Prevalence of β thalassemia carrier state in Sindhi community of Wardha and evaluation of risk factors for β thalassemia trait.

OBJECTIVE To determine the prevalence of β thalassemia in Sindhi community of Wardha and evaluation of risk factors. To give genetic counseling to those diagnosed as carriers. STUDY DESIGN Cross-sectional (prevalence study). SETTING Sindhi community residing in and around Wardha. STUDY PERIOD 18 months. MATERIALS AND METHODS A total of 578 individuals belonging to Sindhi community resid...

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Thrombotic risk factors: basic pathophysiology.

Although venous thrombosis has been traditionally associated with stasis and hypercoagulability, arterial thrombosis is mainly associated with heightened platelet reactivity and damage to the vessel wall. Accordingly, classic risk factors for venous and arterial thrombosis are usually considered distinct. Those for the former include cancer, surgery, pregnancy, and estrogens use, whereas risk f...

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Thrombotic risk factors in pulmonary hypertension.

Thrombotic lesions are consistently observed in chronic thromboembolic pulmonary hypertension (CTEPH) and frequently found in primary pulmonary hypertension (PPH). It remains unknown, however, whether thrombosis is related to defects of the antithrombotic pathway or to previous vascular injury. This study therefore analysed the frequency of both hereditary and acquired thrombotic risk factors i...

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Depression and the affecting factors in patients with β Thalassemia Major having referred to Saravan city thalassemia center in 2017

Abstract Background and Objectives The chronic nature of thalassemia affects different aspects of patients' life and increases depression.The goal of the study was to determine depression and the affecting factors in patients with thalassemia major reffered to Saravan thalassemia center.   Materials and Methods The population of this descriptive analytic study consisted of 60 thalassemic pat...

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Therapeutic approaches in patients with β-thalassemia

Beta-thalassemia (β-thal) is a congenital hemoglobinopathy explained by a decreased level (β+) or absence (βο) of β-globin gene expression. Microcytic hypochromic anemia and various clinical symptoms comprising severe anemia to clinically nonsymptomatic features. Treatment with an ordered blood transfusion and iron chelator agents can decrease transfusion iron overload that causes normal matura...

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ژورنال

عنوان ژورنال: Clinical and Applied Thrombosis/Hemostasis

سال: 2008

ISSN: 1076-0296,1938-2723

DOI: 10.1177/1076029608316170